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    We pile on multiples jackets because a southerners jacket is for 40% style and 60% warmth (the ones that aren’t farmers at least). So we let them ice over and freeze us in for a day or so. We will blow up instagram and facebook with what we are doing saying phrases like “snow much fun”, making our neighbors of the north laugh at us. Because in the south we seem stupid for not being able to function, but when it snows every couple of years, there’s no need to have equipment that clears roads. This fluffy white magic that graces us every few years, knowing that we have been waiting on it. We watch the christmas movies and commercials where someone runs down their swirly stairs in their colonial style homes to peer out the window to a snowy wonderland and a brand new car with a pretty red bow. Christmas Hallmark movies do not exist without a crisp snowy night. We pick out the movies we will watch and know that first thing when we wake up to it we will play for a few hours before coming in and thawing out with said soup. We buy out the space heaters and we get all the ingredients for that crock pot soup we have been waiting to make. We savor snow and remember what we did on those days. “The Blizzard of 93′ “ “All the times we got out of school and it never snowed 1998-2010” “The President’s Day snow of 2010.” “The Snow Apocalypse of 2013” “That time it snowed twice in like a month span December 2017-January2018” We remember those days because there’s nothing quite like them. We get to be with friends and family members we don’t normally get to be cooped up with. The cost of doxycycline, the chief antibiotic used against Lyme disease, rose faster than any other generic drug in the year ending last November. Tick-borne illnesses – including Lyme disease and rapidly rising cases of anaplasmosis – have become more than a worrisome health threat for people and their pets. Valeria Borovkoff, left, guides Mac, a Rheinland Pfalz Saar horse, and Ali Lindsay guides Gambler, a Canadian Sport Horse, along a path toward the stable at the Cedar Crest Farm Equestrian Center in Pine Plains. In 2012, Rhinebeck Equine veterinary practice prescribed bottles of doxycycline to treat Lyme disease for $36 apiece. Now, each can cost $400 or more — and horses may need six 500-tablet bottles for a 30-day treatment. Horses aren't the only ones affected by a rise in the cost of the prime antibiotic used against Lyme disease. Potentially, so are the 300,000 Americans infected yearly. Pet owners are simply more likely to notice the price hike because they are less likely to have insurance to cover it. At the current price, "It's not an option," said Dr. Amy Grice, a Rhinebeck Equine veterinarian, who instead uses a cheaper, but not cheap, alternative drug, minocycline."Doxycycline used to be dirt cheap," said David Bondarenka, a pharmacist for Nekos-Dedrick's Pharmacy in Kingston, which dispenses drugs for animals and people.

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    Une fois les produits finis et le rendez-vous pour l’installation planifié, nous voici rendus à l’étape de l’installation des portes et fenêtres. Nos spécialistes certifiés vous expliqueront le déroulement des travaux afin que vous puissiez comprendre et suivre toutes les étapes du processus. Nos professionnels effectuent l’installation de vos portes et fenêtres dans un environnement sécuritaire pour votre famille et respectent les plus hauts standards de l’industrie. Nous travaillons de pair avec vous pour nous assurer que les produits que nous vous proposons répondent à vos besoins, vos attentes et votre budget. Nos experts s’assurent de vous proposer un devis précis, qui correspond à l’architecture de votre demeure. Nos spécialistes sont certifiés pour tous les types de travaux de livraison et d’installation de portes et fenêtres, et respectent les normes strictes établies par l’industrie de la construction. Nos experts vous offrent une installation minutieuse pour vous assurer une tranquillité d’esprit. "Osteoarthritis is the most common human joint disorder in the world, and in the equine industry it’s the most economically important disease," said Ashlee Watts, DVM, a graduate student at Cornell University, during the 2007 American Association of Equine Practitioners Convention, held Dec. "It’s the primary cause of decreased athletic function and wastage in racehorses." Many medications have been tried to treat this common condition, and Watts discussed the relatively new option of doxycycline for arthritis. Doxycycline is a semisynthetic antibiotic that’s related to tetracycline and has been used in horses since the 1990s. It’s also used to treat Lyme disease, and one study on that disease noted that horses given the medication along with other antibiotics "never went better," despite being negative for Lyme disease, suggesting a possible anti-inflammatory effect. Therefore, researchers decided to investigate its possible use against osteoarthritis. ACVS, associate professor of veterinary clinical sciences at Cornell University, was the principal investigator on the study.) Previous laboratory research found that at concentrations as low as 0.0462 microliters (�g/m L) in synovial (joint) fluid and plasma, doxycycline could inhibit the expression of matrix metalloproteinases 3 and 13 (MMP 3 and 13). Various MMP enzymes have been implicated in osteoarthritic and laminitic disease processes, so inhibiting them might help slow these disease processes. However, antibiotics shouldn’t be used at antimicrobial levels (which are substantially higher than 0.0462 microliters (�g/m L) without good reason, because this might promote antibiotic-resistant bacteria strains. To determine if oral dosing could deliver enough doxycycline (0.0462 �g/m L) to joints without having antimicrobial effects, researchers fed six healthy horses 5 mg/kg (half the recommended antimicrobial dose) every 12 hours via nasogastric tube for two days.

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    • PDF Guidelines for Antimicrobial Use in Horses - ResearchGate.
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    • Doxycycline Antibiotic Might Help Treat Arthritis – The Horse.

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